Saturday, December 13, 2014

Overdominance: The Good, the Bad and the Untermensch

Overdominance also known as Heterozygote advantage, is a very good evidence of the concepts that I have been described. Those concepts are all together in the next picture.

As I have been writing, Species are the result of Natural Selection something like Diploid vs. Haploid Organisms, a result of millions of years of evolution, and that is why before Eukaryotes Species have never existed, because species are also the result of millions of years of evolution.

In this new scheme, Species are the repository of the organism blueprint, physical and psychological, so we may view the Species' Will like the Species' Organism.

Now the old Story, the Story of two Fathers and three Sons, those Fathers are Natural and Sexual Selection, the Sons are the Good, the Bad and the Untermensch! All but one are much loved by each one of their Fathers. They are treated in this manner:
  • the Good - Loved by Sexual Selection, he is in the Gene Pool from the beginning, he is the oldest one. Now and ever Sexual Selection has been taking care of him, is a relationship of profound love and absolute dedication that nothing can reach up;
  • the Bad - Supported by Natural Selection, he is the newcomer, an Intruder, he isn't flushed away by Sexual Selection because doesn't represent any real Entropy to be pushed away, and mainly, because Sexual Selection is permeable to Induction carry out by Natural Selection;
  • the Untermensch - The resulting waste of the Bad, its Entropy is unprompted by the Natural Selection and hated by Sexual Selection. Living in the cold with nothing to save him, is doomed to a path destined to him, a path that leads to persecution and eternal extinction, for ever and ever.
In a more techinal description, the Good is the Fixed Gene, the Bad the Recessive Gene and the Untermensch the Deleterious Gene.

Overdominance is the result of diploidity, a characteristic dominant in Eukaryotes organisms, so a modern trait in evolution, mainly concerning Sexual Selection. So simply explained, overdominance is the introduction of a new gene that has a better fitness than the existing one when paired with it (heterozygous), but is deleterious when paired with itself (homozygous). A good example is the case of Sickle-cell disease, the result of a gene that gives protection against Malaria when alone, but a disease when together. But this is just one example, there are many more examples of overdominance, of recessive genes that are diseases once paired with each together, and so never becoming fixed. The problem is that those examples are only the tip of the iceberg, as well put it in the Fisher's geometric model, in the presence of extreme complexity, evolution has to happen in equally extremely small adjustments, this means that those more fitted genes need to start as a recessive genes, giving room to deleterious homozygous combinations. This reality has been proven in a study titled Heterozygote advantage as a natural consequence of adaptation in diploids, where is stated that:
The larger range of adaptive mutations available to diploids comes with a catch, however; many of these adaptive mutations display heterozygote advantage, and thus will not simply go to fixation.
We argue that adaptation-driven balanced polymorphisms can be an important source of consequential genetic variation. In particular, we believe that the balanced polymorphisms predicted by our model can be associated with human disease. Some of the common disease variants could be mutations that are maintained at high population frequencies because of strong heterozygote advantage, although they are very harmful as homozygotes.
This proves that is the health of the Species that matters, not of its Organisms, a dichotomy that many refuse to view! So, the view of the Good, the Bad and the Untermensch is exclusive to the Species Eyes, organisms have no opinion of their own, because there is only the Species' Will.

This Will permeates all human culture, because is important to maintain the health that really matters, and humans act like actors of a preexisting plot, where conformity to this plot is their only purpose, over the lie of Self Preservation that in reality is only applied to Species. As another study guesses very well:
When you see a difference between your own opinion and that of others, the brain experiences an error signal,” - See more at:
Vasily Klucharev was able to see the physiology of the Species Will, but the real question is always missing, If the Species Health is all it matters, why it would support organisms Free Will? Mainly when this Free Will could be contradictory to the Species Will!

In this will, the only that really exists, the Untermensch needs to be pursued, and you don't need to look further to see this persecution. Albinos, a result of overdominance, are being so, like the next article shows very well.
In the rural areas of Tanzania, men, women, and children with albinism--a lack of pigment that makes them appear glaringly white--are waging an extensive human rights campaign against communities who routinely attack them for their hair or body parts, used in potions to attract wealth and good luck. -

This kind of persecution is heavily associated with superstition, the root of any religion, and that is why that despite all efforts of science to end superstition, it prevails, because this superstition is no more than the excuse that species give to organisms act the way they are supposed to. If you think that this is an isolated case you are wrong. Superstition relates to all situations of difference or non conformity with the standard. Witchcraft accusations against children is just one way of persecution, another is traditional Folklore, like Trolls or the Changeling, where the theme of the swapped child is common among medieval literature and reflects concern over infants thought to be afflicted with unexplained diseases, disorders, or developmental disabilities.

This folklore is transported to our days, in movies or pop icons, like one Troll of Rage Comic characters, were the Forever Alone, not surprisingly, is the most popular.

This and the successful Lord of the Rings are cultural examples of the Species Will against the Untermensch, where individuals are right in clamming innocence due to the fact of having no will in this matter (or any other).

Like Shame in Sex, that I talked about in a post before, the Untermensch is also wrongly associated to ideologies in particularly with Nazism, not realizing that Nazism doesn't borrow only its symbols from ancient folklore, like the Swastika or the SS symbol, it also borrow all the feelings already existing then and that continue to exist now, feelings that you may well guess having one single source.

These feelings that exist to be interpreted and followed by humans, are the ones that glorify all individuals with high levels of conformity, being under the Species Wing gives you a special aura.

Unfortunately Species are very picky and ruthless against non conformity, it has successfully been managing its "guardians" against it. So, in the so called civilized world, and despite being very civilized, the species guardians do their work as they do in Africa. And is not difficult to have news of some of them, now named Bullies. Yes in bullying may be some friendly fire, but we shouldn't delude ourselves, bulling has a very well defined purpose that is not just about young fellows as Workplace Bullying shows in a recent study, the victims are well profiled:
Over the years, much attention has been devoted to understanding counterproductive work behavior (CWB) and its related concepts. Less is known, however, about whether certain employees find themselves more than others to be the targets of CWB. To examine this issue, we tested a model that positioned CWB receipt as a function of employees' personality (neuroticism, agreeableness), their appearance (physical attractiveness), and the negative emotions felt toward those employees by their coworkers. Two studies using multiple sources of data revealed that disagreeable and physically unattractive employees received more CWB from their coworkers, coworker negative emotion felt toward employees was associated with CWB receipt, and the relationship between employee agreeableness and CWB receipt was due, in part, to coworker negative emotion. - Beauty, Personality, and Affect as Antecedents of Counterproductive Work Behavior Receipt
To be clear and rest no doubts:
In addition to personality, we examined physical attractiveness, positing that attractive employees would be less likely to elicit negative emotion in their coworkers and receive CWB than unattractive employees. Theories of social acceptance stipulate that characteristics valued by society include both communal qualities such as kindness and warmth (i.e., agreeableness) and superficial qualities such as beauty (Anthony, Holmes, & Wood, 20007). Indeed, research on bullying among school-age children has revealed that victims of bullying are more likely to perceived as physically unattractive by their peers (e.g., Sweeting & West, 2001; see also Olweus, 1978). Thus, by including personality (neuroticism and agreeableness) and appearance (physical attractiveness), our model acknowledges that in predicting the receipt of CWB, it likely is “what's on the inside” and “what's on the outside” that counts. - Beauty, Personality, and Affect as Antecedents of Counterproductive Work Behavior Receipt
So, while things continue to be seen as flat, while we ignore the trinity of the Eukaryotic model, we will continue to make the same mistakes, and search for causes in the wrong place.

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